NAD+ science & education

NAD Educational Videos

Everything you need to know about NAD IV. Dr. Payam Hakimi explains the many benefits and mechanism of NAD and talks about what it feels like to receive an infusion in this 15min video.

Dr. Ramsey interviews an patient who suffers from Alzheimer’s and the benefits he received with IV NAD+ therapy. 

Paul talks about his experience with IV NAD and it helped his chronic fatigue as well as his mood. 

Dr. Brad Stanfield reviews current data demonstrating the effects of aging and exercise on NAD+ levels. He highlights the importance of exercsise in order to activate the salvage pathway and boost natural NAD+ levels. 

NAD- Scientific Studies

NAD+ is directly involved with our energy metabolism by supporting mitochondrial function in the cell. Mitochondria are the powerhouse of the cell that convert our food into energy units. It is no surprise that NAD+ treatments can have a positie effect of disorders like chornic fatigue, fibromyalgia, and lyme disease.

Although more clinical studies as needed, the data thus far is promising.

NAD+ can restore age-related muscle deterioration, research finds – Jan 2021

Kynurenine Pathway Pathologies: do Nicotinamide and Other Pathway Co-Factors have a Therapeutic Role in Reduction of Symptom Severity, Including Chronic Fatigue Syndrome (CFS) and Fibromyalgia (FM) – July 2013

Therapeutic Potential of NAD-Boosting Molecules: The In Vivo Evidence – March 2018

Preclinical and clinical evidence of NAD+ precursors in health, disease, and ageing – Sept 2021

Therapeutic effects of oral NADH on the symptoms of patients with chronic fatigue syndrome – Feb 2019

Mental health disorders are incredibly complex and multifaceted. Patients have reported improements of mood, with dercrease in axnxiety and depression symptoms, after recieving NAD treatments.

Depression, epsecially in the context of chronic disease and/or aging, is believed to confer a signficant better to quickly feeling better. Clinical studies are currently underway and the data so far is promising.

Study Links Depression to Reduced Levels of NAD+ – Producing Protein – Oct 2021

Nicotinamide mononucleotide ameliorates the depression-like behaviors and is associated with attenuating the disruption of mitochondrial bioenergetics in depressed mice – Feb 2020

Nicotinamide, a vitamin B3 ameliorates depressive behaviors independent of SIRT1 activity in mice – Nov 2020

There is increasing evidence of the benefits NAD offer when treating substance abuse.

Recent studies have shown NAD, specifcally for treating alcohol and opiate abuse, reduces cravings, reduces relapse episodes and shows potential for long-term therapy in maintaining sobriety.

Intravenous Administration of Nicotinamide Adenine Dinucleotide Significantly Reduces Self Report Craving Ratings Associated with Opiate and Alcohol Withdrawal*- March 2020

Sobriety and Satiety: Is NAD+ the Answer? – May 2020

Nicotinamide Adenine Dinucleotide (NAD+) and Enkephalinase Inhibition (IV1114589NAD) Infusions Significantly Attenuate Psychiatric Burden Sequalae in Substance Use Disorder (SUD) in Fifty Cases – July 2022

In process…