Depression treatment

Fast Acting Depression Treatment

There is no shame.

Ketamine has a robust and rapid effect on depression, with many patients reporting immediate relief shortly after their first ketamine infusion session.

Symptoms often include:
Depression ketamine treatment

Ketamine is not the only treatment offered!

During your initial intake, we perform a comprehensive personal review focusing on the biopsychosocial model of medicine.

We strive to find the root cause of your problems and help you with changes in mindset, behavior, and medications/supplements that will allow you to live the life you want.

Other IV Therapy modalities, such as NAD, can be used in conjunction or instead of ketamine depending on your specific situation.

Ketamine has a rapid effect on the brain

The vast majority of research conducted on the effects of ketamine on mental health has been for the treatment of depression, specifically treatment-resistant depression (TRD). A scientific review conducted in 2014 found that over 70% of patients treated with IV ketamine responded to treatment. There have been numerous studies in the last two decades that indicate ketamine is not only effective but fast-acting. If you would like to watch some entertaining educational videos and/or read some relevant scientific studies on the benefit and use of ketamine therapy, then please visit our science & education page.

Ketamine is NOT experimental; it is utilized off-label like 45% of psychiatric medication used in the United States today. Because of the safety and effectiveness of the drug, it is endorsed by both the APA (American Psychiatric Association) and the NIMH (National Institute of Mental Health) as a treatment for depression.

If you have tried other traditional treatments that have failed to provide the relief you are looking for, then ketamine therapy could be right for you. Please contact us to schedule your free-15min phone consultation with Dr. Mallek today.

There is Hope

Restore Your Life

The 3-minute interview on the right is from a patient that experienced great benefit from Ketamine treatments.

In this interview, Dr. Mandel, an anesthesiologist from Los Angeles, that pioneered these treatments long ago talks about the potential benefits and the procedures followed at his clinic.

Dr. Mallek has met Dr. Mandel and has learned a great deal from him. Our clinic operates similarly.

How Does Ketamine Help With Depression?

Ketamine works by a similar mechanism for most mental health disorders. Since it modulates glutamate activity and glutamate is present in 90% of excitatory brain connections, the applications are broad.

Ketamine is known to act on the NMDA receptor as an antagonist, meaning it blocks the action of that reception. In addition, ketamine also acts on the AMPA receptor (an action of R-ketamine that is missing from the nasal spray S-ketamine). The downstream effect of the action on both these receptors results in modulating signals and decreasing the amount of glutamate, a major neurotransmitter inside the brain, as previously mentioned.

With the inhibition of glutamate, you get an increase in brain-derived neurotrophic factor (BDNF). This is huge since it leads to the formation of new neurons (neurogenesis) and new pathways (synaptogenesis). Ketamine works like no other medication.

In addition to its action on NMDA and AMPA as stated above (which is thought to be the primary mechanism), it is also effective on aminergic, opioid, and cholinergic systems. This could also contribute to behavioral and neural network changes, which is exactly what we want.

This unique mechanism contributes to ketamine’s fast action. Conventional antidepressants, which increase the number of neurotransmitters available, such as serotonin, take multiple weeks to start taking effect, whereas ketamine starts working within hours.

The effects of ketamine are rapid following an infusion; however, a complete treatment series, coupled with integration sessions during which we will implement beneficial behavioral changes, holds the greatest potential for long-lasting relief.

The majority of studies are on major depressive disorder (MDD) and treatment-resistant depression (TRD). There is increasing literature and evidence for the application of this drug to other mental health disorders such as bipolar, PTSD, and anxiety disorders.

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During Your Ketamine Infusion

We strive to ensure that all our patients feel as comfortable as possible in their private rooms during treatment.

Many of our patients have reported experiencing a ‘dissociation’ effect, which contributes to the effectiveness of their treatment and yields a positive response to ketamine therapy for a significant number of individuals.

This dissociation phenomenon is a normal part of the treatment process. During your intake, we will provide you with a tour, giving you a better understanding of what to anticipate. If you would like to familiarize yourself with the process beforehand, please visit our Patient Prep page.

Relevare is a ketamine clinic with an environment structured to be both welcoming, comforting, and safe. We have a fully equipped crash cart, oxygen, and all our providers are ACLS-certified. You will be monitored at all times and receive individualized and compassionate care during your infusion treatments.

There Is Hope

If traditional treatments have failed you, know that there is hope. Ketamine has helped countless many who thought there was no hope left. 

It is time to get out of your head and start to live a life more dignified and fulfilled life. 

Contact Relevare today and schedule your free 15min phone consultation with Dr. Mallek. 

A Comfortable & Welcoming Environment

We strive to ensure that all of our patients feel welcome and as comfortable as possible during their visit. We provide private rooms for each patient during all our ketamine intravenous treatments. Our patients always remain in a safe atmosphere assisted by our professional medical staff members that provide one-on-one care at all times.


At Relevare, we are dedicated to making you feel heard, taken care of, and relaxed.

Ready To Start Your New Journey In Life?

Ready to get started? Call us today for your free phone consultation.