Depression treatment
Fast Acting Depression Treatment
There is no shame.
Symptoms often include:
- Feelings of sadness, tearfulness, emptiness or hopelessness.
- Loss of interest or pleasure in most or all normal activities, such as sex, hobbies or sports.
- Sleep disturbances, including insomnia or sleeping too much.
- Tiredness and lack of energy, so even small tasks take extra effort.
- Reduced appetite and weight loss or increased cravings for food and weight gain.
- Anxiety, agitation or restlessness.
- Slowed thinking, speaking or body movements.
- Feelings of worthlessness or guilt, fixating on past failures or self-blame.
- Trouble thinking, concentrating, making decisions and remembering things.
- Frequent or recurrent thoughts of death, suicidal thoughts, suicide attempts or suicide.
- Unexplained physical problems, such as back pain or headaches.

Ketamine is not the only treatment offered!
During your initial intake, we perform a comprehensive personal review focusing on the biopsychosocial model of medicine.
We strive to find the root cause of your problems and help you with changes in mindset, behavior, and medications/supplements that will allow you to live the life you want.
Other IV Therapy modalities, such as NAD, can be used in conjunction or in lieu of ketamine depending on your specific situation
Ketamine has a rapid effect on the brain
The vast majority of research conducted on the effects of ketamine on mental health has been for the treatment of depression, specifically treatment-resistant depression (TRD). A scientific review conducted in 2014 found that over 70% of patients treated with IV ketamine responded to treatment. There have been numerous studies in the last two decades that indicate ketamine is not only effective but fast-acting as well. If you would like to watch some entertaining educational videos and/or read some relevant scientific studies on the benefit and use of ketamine therapy then please visit our science & education page.
Ketamine is NOT experimental, it is utilized off label just like 45% of psychiatric medication used in the United States today. Because of the safety and effectiveness of the drug it is endorsed by both the APA (American Psychiatric Association) and the NIMH (National Institute of Mental Health) as a treatment for depression.
If you have tried other traditional treatments that have failed to provide the relief you are looking for then ketamine therapy could be right for you. Please contact us to schedule for free 15min phone consultation with Dr. Mallek today.
There is Hope
Restore Your Life
The 3-minute interview on the right is from a patient that experienced great benefit from Ketamine treatments.
In this interview, Dr. Mandel, an anesthesiologist from Los Angeles, that pioneered these treatments long ago talks about the potential benefits and the procedures followed at his clinic.
Dr. Mallek has met Dr. Mandel and has learned a great deal from him and our clinic operates in a similar fashion.
How Does Ketamine Help With Depression?
Ketamine works by a similar mechanism for most mental health disorders. Since it modulates glutamate activity, and glutamate is present in 90% of excitatory brain connections, the applications are broad.
Ketamine is known to act on the NMDA receptor as an antagonist, meaning it blocks the action of that reception. In addition, ketamine also acts on the AMPA receptor (an action of R-ketamine that is missing from the nasal spray Esketamine). The downstream effect of the action on both these receptors results in modulating signals and decreasing the amount of glutamate, a major neurotransmitter inside the brain as previously mentioned.
With the inhibition of glutamate, you get an increase in brain-derived neurotrophic factor (BDNF). This is huge since it leads to the formation of new neurons (neurogenesis) and new pathways (synaptogenesis). Ketamine works, unlike no other medication.
In addition to its action on NMDA and AMPA as stated above (which is thought to be the primary mechanism), it is also effective on aminergic, opioid, and cholinergic systems. This could also contribute to behavioral and neural network changes, which is exactly what we want.
This unique mechanism contributes to ketamine’s fast action. Conventional antidepressants, which increase the number of neurotransmitters available, such as serotonin, take multiple weeks to start taking effect whereas ketamine starts working within hours.
The effects of ketamine are fast following an infusion however a full treatment series coupled with integration sessions where we will implement helpful behavioral changes has the highest potential for long-lasting relief.
The majority of the studies are on major depressive disorder (MDD) and treatment-resistant depression (TRD). There is increasing literature and evidence for the application of this drug to other mental health disorders such as bipolar, PTSD, and anxiety disorders.
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During Your Ketamine Infusion
We strive to ensure all of our patients feel as comfortable as possible in their private rooms during treatment.
A number of our patients refer to a “dissociation” effect. This disconnection effect aids your treatment and delivers a positive response to your ketamine therapy for many patients.
This is all an ordinary component of the treatment. During your intake, we will show you around and you will have a better idea of what to expect. If you would like to get an idea of the process beforehand then please visit our Patient Prep page.
Relevareis a ketamine clinic with an environment structured to be both welcoming, comforting, and safe. We have a fully equipped crash cart, oxygen, and all our providers are ACLS-certified. You will be monitored at all times and receive individualized and compassionate care during your infusion treatments.
There Is Hope
If traditional treatments have failed you know that there is hope. Ketamine has helped countless many who thought there was no hope left.
It is time to get out of your head and start to live a life more dignified and fulfilled life.
Contact Relevare today and schedule your free 15min phone consultation with Dr. Mallek.

A Comfortable & Welcoming Environment
We strive to ensure that all of our patients feel welcome and as comfortable as possible during their visit. We provide private rooms for each patient during all our ketamine intravenous treatments. Our patients always remain in a safe atmosphere assisted by our professional medical staff members that provide one-on-one care at all times.
At Relevare, we are dedicated to making you feel heard, taken care of, and relaxed.
Ready To Start Your New Journey In Life?
Ready to get started? Call us today for your free phone consultation.